IPANEMA project

Casc4de is engaged in a new project IPANEMA
supported by ADEME, The French Agency for Ecological Transition .

A collaboration leaded by INRAE, a research institute working for the coherent and sustainable development of agriculture, food and the environment,
And dedicated to investigations of PFAS soils pollution.

Extreme resolution & sensitivity in FTICRMS

Phase sensitive 2D in absorption mode allows extreme resolution and sensitivity in FTICRMS.

A collaboration between Maria van Agthoven, Kathrin Breuker, Marc-André Delsuc
CASC4DE, IGBMC, University of Strasbourg & Leopold-Franzens Universität Innsbruck


CASC4DE , member of the EU FT-ICR MS network, has developed remote processing tools and has set up a data exchange platform. These enable you to process & record your results and associate them with those generated within the EUFTICR MS project framework.


T2 - Inverse Laplace Transform

Explore your porous materials with T-ILT

with an easy and fast
software to analyse your data


Automatize your pharmacophoric deconvolution for plant extracts with Plasmodesma.
Fast and intuitive identification of active compounds from natural extracts with an interactive user-friendly graphical web application


CASC4DE has developed efficient NMR and Machine Learning techniques for analysis, detection , characterization, quantification and identification of fluorinated compounds (including PFAS pollutants) from NMR spectra.

When quantum computing meets chemistry issue.

Prof Dominique Sugny and Dr Steffen Glaser, OCT specialists from ICB Laboratory, collaborated with Casc4de scientists for a deeper understanding of experimental techniques in analytical sciences.

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About Us

CASC4DE , created in 2014 by Marc-André Delsuc and Bruno Kieffer, is a company specialized in the development of analytical methods along with software and data engineering.

CASC4DE develops innovative solutions to tackle the challenges of managing and processing large set of analytical data by combining interdisciplinary skills in the biochemistry, mathematical and data-science fields. Furthermore the company carries out its R&D in the spirit of open science (F.A.I.R. data if possible) and open-source (free and independent software).

CASC4DE also offers services to answer analytical client’s issues. It proposes multi-analytic approaches with access to advanced Nuclear Magnetic Resonance (19F fluorine, 2D, 3D NMR) or Mass Spectrometry (FTICR MS, 2D FTMS).


Our expertise

Analytical methods & data engineering: count on our expertise in NMR & High Resolution Mass Spectrometry

Biophysics / Analytics
Nuclear Magnetic Resonance
High Res Mass Spectroscopy

Custom services for analytical methods development using biophysics instruments

Custom analytical services

Analytical services: testing, analysis, control

Chemicals testing
Physico-chemical analysis
Environmental analysis 
Impurity control

Software engineering Mathematics, machine learning, massive number crunching

Machine Learning
Compressed Sensing
Massive number crunching

Software & Data engineering / Signal processing

Signal Processing
Innovative high-speed data processing algorithms and techniques

Custom software development, Software and data engineering

Custom Software Development
Embeddable packaged software web server

Software engineering, Big data and Science

As almost all industrial sectors, science is facing some real data challenges.

Indeed instruments, sensors and pictures collect massive amounts of information and raw data, structured or not. Due to the increasing size of data, current technologies require new approaches for an optimized exploitation ! Computation has to be done where the data is and should to be done locally.

A significant amount of data is generated in real time. Treatment and handling must be performed « on-the-fly », usually without the possibility of archiving the data flow. Moreover, day-to-day datasets are often disparate, noisy and prone to be corrupted by outliers and artefacts. Despite this complexity, our new algorithms, mathematical approaches and methodological techniques allow more robust, faster and automatized data-flows.


Today CASC4DE builds innovative hardware-enhanced capabilities and softwares to accelerate your research and extract hidden insights from your data flow.

Analytical methods Software engineering Big data


Analytical methods Software engineering NMR
Analytical methods Software engineering Mass Spectrometry
Analytical methods Software engineering HumanHealth

Analytical methods Custom Services

CASC4DE offers analytical services including, but not limited to:

-Chemicals Testing

  • Routine analyses NMR 1D, 2D, IR, MS for REACH compliance.
  • Detection, identification, characterisation and quantification of chemical species, for example:
    • small molecules identification (structure elucidation and purity),
    • purity control (products quality or security).

-Physico-chemical measurement

  • Oxyethylenation degree
  • Crosslinking rate.

-Environmental pollutants analysis  (fluorinated, PFAS…)


CASC4DE also provides support for analytical methods implementation using:

-Ultra High Resolution Mass Spectrometry FTICR mass analyser (10 to 100 fold higher mass resolving power and accuracy than any other MS techniques)

-NMR spectroscopy applications

Analytical methods Software engineering Custom services

Your benefits

Save time / Analytical methods Software engineering

Save time 

Casc4de dual expertise Analytical methods Software engineering

Dedicated dual expertise
in analytical methods (NMR, High Res MS) and software & data engineering

Big data bottleneck

Remove the Big Data bottleneck
Speed up your results flow

Analytical methods Software & Data engineering Software applications

Software Applications,
Technology Solutions created uniquely for Your Needs

Our partners

Institut de Génétique et de Biologie Moléculaire et Cellulaire.
Université de Strasbourg
Grand Est
Agence Nationale de la Recherche

Discuss your project with us