By CASC4DE February 27, 2025

Per- and polyfluoroalkyl substances (PFAS), often dubbed “forever chemicals” due to their extreme persistence in the environment, are now found in our drinking water supplies and the implications are alarming. These chemicals, used for decades in industrial processes and consumer goods, are now linked to serious health risks, including various cancers and endocrine disruptions.
🔬 PFAS and Cancer: Alarming New Findings
A recent study by the USC Department of Population and Public Health Sciences, published in the Journal of Exposure Science & Environmental Epidemiology, found that PFAS in drinking water may be responsible for 4,626 to 6,864 new cancer cases per year in the U.S. alone.
Researchers analyzed national water monitoring data (UCMR3 and UCMR5) alongside cancer incidence statistics and exposure models. They focused on six common PFAS and their association with five types of cancer, including: Kidney cancer, Testicular cancer, Prostate cancer, Ovarian cancer, Non-Hodgkin’s lymphoma.
📊 Key Findings:
- Cancer Risk: Even at low concentrations, PFAS exposure was significantly linked with increased cancer risks—particularly kidney and testicular cancers.
- Sex Differences: Men appear to be at higher risk than women for kidney and prostate cancers.
- Hotspots: Individuals living near industrial sites or areas with heavy firefighting activity face much higher exposure risks.
⚠️ Experts warn that these figures likely underestimate the true public health burden, as only a fraction of all PFAS are currently monitored.
🏥 Beyond Cancer: Additional Health Risks
PFAS exposure is associated with several other serious health issues:
- 🔄 Endocrine Disruptions: Thyroid disorders, infertility
- 🦠 Immune System Impairment: Increased infections, reduced vaccine response
- 🤰 Pregnancy Complications: Premature births, low birth weights
🌍 A Growing Global Concern
PFAS contamination is not just a U.S. issue.
- In England, hundreds of water samples have been found to exceed safe limits for PFAS.
- In France, new PFAS regulations will ban their use in cosmetics, textiles, and ski waxes starting in 2026, with a full ban on all textiles by 2030.
🚀 What’s Being Done?
- Some countries are lowering safe thresholds for PFAS in drinking water.
- New PFAS-free alternatives are being explored in consumer products, as highlighted by Ian Cousins and Romain Figuière in “Overview of Potential Alternatives for the Multiple Uses of PFAS”.
- Water treatment innovations are being developed to remove PFAS from contaminated sources.
⚠️ Public Health at a Crossroads
The contamination of our drinking water poses a significant and growing threat to public health. The time to act is NOW:
✔ Stronger regulations
✔ Investment in clean water technology
✔ Transition to PFAS-free alternatives
💡 Stay informed and remember that when it comes to “forever chemicals”, prevention is the best cure!